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No, a man who "transforms" into a woman, will never be a woman, biologically speaking. Physiologically he will always be a man, and he will only be able to imitate the "behaviors" that he believes are feminine, when in fact there are no feminine or masculine behaviors, they are not real subjectively.
So, no, a man who wants to be a woman will never be either physically or in anything else, since he will never understand the complexity of the imaginary with respect to what it means to be a woman in society, he can only imitate what he believes is to be a "woman". And the same with women who want to be men.